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COLCRYS has been shown to both reduce gout attack pain—in some patients by the end of their first day on COLCRYS—and to help prevent gout flares when starting a medicine to lower uric acid levels.

Individual results may vary.

COLCRYS: Focusing on gout attack pain

How COLCRYS works

  • While the effect of colchicine (the main ingredient in COLCRYS) has been studied, it is not known exactly how colchicine works to treat gout flare pain
  • COLCRYS may prevent the body’s various immune responses to uric acid crystals, which can help reduce gout flare pain
  • COLCRYS is not a general pain medicine and should not be taken to treat pain related to other conditions

COLCRYS does not treat high uric acid levels (the cause of gout), and has not been shown to prevent joint deformities and tissue destruction.

Painful gout flares are due to the body's immune response to uric acid buildup in joints

The Gout Flare Tracker can help you tell your doctor how you are feeling

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The Gout Flare Tracker can help you tell your doctor how you are feeling

Gout Flare Tracker

Eligible patients could pay as little as $15 for a COLCRYS prescription

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COLCRYS can help treat gout attacks and prevent future flares

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Important Safety Information for COLCRYS (colchicine, USP)

  • COLCRYS can cause serious side effects or death if levels of COLCRYS are too high in your body. Taking certain medicines with COLCRYS can cause your level of COLCRYS to be too high, even at recommended doses, especially if you have kidney or liver problems.
  • Tell your healthcare provider about all your medical conditions and all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements, and if you consume grapefruit juice.
  • Fatal overdoses, both accidental and intentional, have been reported in adults and children who have ingested colchicine. Keep COLCRYS out of the reach of children.
  • COLCRYS can also cause serious muscle problems and blood disorders even when taken as directed. You have a higher chance for muscle problems if you are elderly, are taking certain other medicines with COLCRYS, or have kidney problems.
  • Tell your healthcare provider if you have any side effect that bothers you or that does not go away.
  • The most common side effects in people who have gout flares are diarrhea (23%) and throat pain (3%).


COLCRYS (colchicine, USP) 0.6 mg tablet is a prescription medicine used in adults to prevent and treat gout flares.

COLCRYS is not a pain medicine and should not be taken to treat pain related to other conditions.

Individual results may vary.

Please see the complete Prescribing Information and Medication Guide and talk to your healthcare professional.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.