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COLCRYS has been shown to help prevent gout flares when starting a medicine to lower uric acid levels.

Individual results may vary.

Dosing to help prevent future flares

COLCRYS with uric acid–lowering medicine

If you are starting treatment with a uric acid–lowering medicine, talk to your doctor about adding COLCRYS to help prevent gout flares.

When you start taking a medicine to lower your uric acid level, you may actually experience more frequent painful gout flares because of the way these medicines work in your body.

Daily dose: 1 or 2 tablets per day
  • Be sure to take COLCRYS exactly as directed by your doctor
  • COLCRYS may be taken with or without food

Grapefruit and grapefruit juice may also interact and should not be consumed during COLCRYS treatment

If you have conditions such as kidney or liver problems, or are taking certain medicines, your doctor will need to adjust your COLCRYS dosage.

COLCRYS dosing up to 2 tablets per day for gout flare prevention

  • Your doctor may prescribe COLCRYS along with uric acid–lowering medicine
  • When COLCRYS is taken to prevent flares—along with a uric acid–lowering medicine—1 or 2 tablets per day are recommended

COLCRYS does not treat high uric acid levels (the cause of gout), and has not been shown to prevent joint deformities and tissue destruction.

For complete information about the side effects of COLCRYS, see Safety Profile & Side Effects.

To help prevent future flares stay with 1 or 2 tablets

The Gout Flare Tracker can help you tell your doctor how you are feeling

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The Gout Flare Tracker can help you tell your doctor how you are feeling

Gout Flare Tracker

Eligible patients could pay as little as $15 for a COLCRYS prescription

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Important Safety Information for COLCRYS (colchicine, USP)

  • COLCRYS can cause serious side effects or death if levels of COLCRYS are too high in your body. Taking certain medicines with COLCRYS can cause your level of COLCRYS to be too high, even at recommended doses, especially if you have kidney or liver problems.
  • Tell your healthcare provider about all your medical conditions and all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements, and if you consume grapefruit juice.
  • Fatal overdoses, both accidental and intentional, have been reported in adults and children who have ingested colchicine. Keep COLCRYS out of the reach of children.
  • COLCRYS can also cause serious muscle problems and blood disorders even when taken as directed. You have a higher chance for muscle problems if you are elderly, are taking certain other medicines with COLCRYS, or have kidney problems.
  • Tell your healthcare provider if you have any side effect that bothers you or that does not go away.
  • The most common side effects in people who have gout flares are diarrhea (23%) and throat pain (3%).


COLCRYS (colchicine, USP) 0.6 mg tablet is a prescription medicine used in adults to prevent and treat gout flares.

COLCRYS is not a pain medicine and should not be taken to treat pain related to other conditions.

Individual results may vary.

Please see the complete Prescribing Information and Medication Guide and talk to your healthcare professional.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.